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IV Fluids, I.V. solutions, Intravenous fluids, Normal Saline (NS, 0.9NaCl, or NSS), Lactated Ringers (LR, Ringers Lactate, or RL), Dextrose 5%, Normal Saline (Half Normal Saline, 0.45NaCl, .45NS), IV Fluids & Dialysis products - LVP/SVP Volume Parenteral

 

I V Fluids

Intravenous therapy (IV) is therapy that delivers fluids directly into a vein. The intravenous route of administration can be used both for injections, using a syringe at higher pressures; as well as for infusions, typically using only the pressure supplied by gravity. Intravenous infusions are commonly referred to as drips.

The intravenous route is the fastest way to deliver medications and fluid replacement throughout the body, because they are introduced directly into the circulation. Intravenous therapy may be used for fluid volume replacement, to correct electrolyte imbalances, to deliver medications, and for blood transfusions.

Infusion therapy as a basic toll of modern medical care enables the physician to restore and stabilize homeostasis states quickly and completely. In nursing homes and hospital where patients are suffering from acute dehydration or considerable debilitating conditions, the intra venous fluids are used as I.V. drips. The basic function of I.V. fluids is to replenish the body fluids. Although there are number of I.V. fluids, but generally three types of I.V. fluids are used in hospitals as I.V. drips. 1. Dextrose injection fluid. 2. Dextrose and sodium chloride injection fluid. 3. Sodium Chloride injection solution (Saline solution). Dextrose solution is used during postoperative period when sodium extraction of 10-15% are used as diuretic for increasing in urine flow. Saline solution is used when large amount of sodium has been lost by vomiting or by gastric or intestinal duodenal aspiration or through an alimentary fistula. Dextrose monohydrate is used as supplement to cow’s milk in part of feeding. Hypertonic dextrose solution (25-50%) is in medical treatment partly because they are believed to strengthen heart muscles. Hypertonic solutions are used in intravenous injection to relieve intractable pressure in-patient with hydrocephalus and meningitis. The drug industry has now achieved an impressive growth during the last four decades of planning and development. These I.V. fluids are the best alternative, which can yield sudden result in the health of a Patient by replenishing the body fluids.

Intravenous solutions have evolved with technologies and designs improving their overall functionalities. There are several combinations of packaged intravenous products that have come up in recent years. Manufacturers are introducing IV fluids and compounds that can be mixed with other liquid medicines and solutions for IV administration. The aforementioned factors will continue to drive the global intravenous (IV) solution market.  Some of the factors that are having positive impact on the growth of the intravenous (IV) solution market include increased prevalence of chronic disorders and growing popularity of IV led treatments and therapies intended towards curing cance.

Uses and Applications

There are main ranges of application of highly specialized intravenous infusion solutions:

• Treatment of discarded water and electrolyte metabolism, especially in severe cases.

• Therapy of acid base in balances.

• The volume substitution and volume replacement in surgery of accident victim suffering blood loss.

• Paratral nutrition for severally ill and post-operative patients.

Aqueous isotonic injection (5%) of dextrose is given as intravenous injections to increase the column of circulating blood in the shocks and hemorrhages and to counteract dehydration. When it is desired to replace excessive salt loss also glucose is injected along with sodium chloride. Intravenous fluids can also be used as a route of medication administration. If a doctor wants to delI.V.er a small amount of medication over an extended period of time, it can be dissolved in a bag of intravenous fluids and set on an infusion pump which delivers the medicated fluid directly into the blood.

They are also commonly used to assist with surgical recovery; people who receive fluids after surgery tend to experience better recovery than people who do not.

Global Intravenous Solutions Market Trends:

Over the past few years, the prevalence of hectic work schedules and unhealthy lifestyles has increased across the globe. The consequent decline in physical activity and proper nutrition has led to a rise in the incidences of chronic diseases, which in turn has boosted the demand for intravenous solutions. Besides, there has been significant growth in the production of IV fluids, particularly in developed countries. For instance, it was reported that due to the shortage of IV saline, the US Food and Drug Administration (FDA) and other market. The intravenous fluid bags market size will grow at a CAGR of 6% at an incremental growth of $ 667.51 MN during 2020-2024.

The increasing prevalence of chronic diseases such as the rise of cholera and growing acceptance of vitamin c intravenous for colorectal cancer are the major drivers propelling market growth. However, the presence of stringent government regulations, rising continuous demand for IV solutions in the US, and increasing vitamin C intravenous therapy prices constrain the growth of the market.

The rising number of surgeries, the need for a faster route of drug administration, growing preference for single-dose administration of vaccines and drugs, and an increase in local manufacturing is expected to drive the market for LVP. Parenteral route of administration helps provide an accurate dose of medication as the majority of the drug is directly absorbed in circulation, bypassing the gastrointestinal tract.

The drug serum level increases rapidly through parenteral administration. For instance, postoperative parenteral nutrition induces a substantial increase in serum leptin within six hours and helps reach a rise of more than four folds within 14 hours. Moreover, parenteral administration of ascorbate (Vitamin C) decreases the growth rate of murine hepatoma. However, oral administration of the same dosage does not exhibit similar anti-tumoral effects.

Advantages of BFS Technology:

Blow-fill-seal technology enables the manufacture of preservative-free single-unit doses. PreservatI.V.es are recognized as potentially harmful to the sensitive mucosae of the eyes, nose, and lungs, so this is an enormous benefit to sensitive patients. Another advantage of unit-doses is that they ensure that the patient takes the correct amount of product, especially when dealing with highly potent compounds, i.e. those therapeutically active at a low concentration.

Sterile unit-doses are portable and easy to use individually, excellent properties for today’s active lifestyles. Blow-fill-seal (BFS) single doses are an ideal solution for use in ophthalmology, respiratory diseases, rhinology, and antisepsis and wound care. Blow-fill-seal technology reduces personnel intervention making it a more robust method for the aseptic preparation of sterile pharmaceuticals. BFS is used for the filling of vials for parenteral preparations and infusions, eye drops, and inhalation products. Generally the plastic containers are made up of polyethylene and polypropylene. Polypropylene is more commonly used to form containers which are further sterilized by autoclaving as polypropylene has greater thermo stability.

Blow Fill and Seal technology is mainly used for pharmaceutical solutions. The examples of pharmaceutical solutions that can be packaged are injectable solutions, antibiotics, ophthalmological drops, suspensions, infusion solutions, solutions for dialysis, solutions for irrigation and solutions for hemofiltration. The basic concept of BFS is that a container is formed, filled, and sealed in a continuous process without human intervention, in a sterile enclosed area inside a machine. Thus this technology can be used to aseptically manufacture sterile pharmaceutical liquid dosage forms.

The process is multi-stepped: first, pharmaceutical-grade plastic resin is vertically heat extruded through a circular throat to form a hanging tube called the parison. This extruded tube is then enclosed within a two-part mould, and the tube is cut above the mould. The mould is transferred to the filling zone, or sterile filling space, where filling needles (mandrels) are lowered and used to inflate the plastic to form the container within the mould. Following the formation of the container, the mandrel is used to fill the container with liquid. Following filling the mandrels are retracted and a secondary top mould seals the container. All actions take place inside a sterile shrouded chamber inside the machine. The product is then discharged to a non-sterile area for labeling, packaging and distribution. The process begins with the Extrusion of plastic granules in the form of a hot hollow pipe of molten plastic called a parison.

The following step is the Blow molding of the container from the plastic granule. The parison is closed between the mould, and the container gets formed either by blowing sterile compressed air or by vacuum or by using vacuum as well as blowing. The container assumes the shape of the cavity in the mould. The container thus produced is open from the top and in its top part, the plastic is still hot and in molten state until the subsequent steps of filling and container sealing.

Features:

1. 100% film utilization: No waste edge between bags, reducing both material and energy consumption.

2. Special I.V. bag design: each bag saves 10mm film than others.

3. Reliable heating and welding system: Leakage rate less than 0.03%.

4. Quick changeover: 0.5-1 hour to switch from one size to another.

5. Stable transmission system: only needs 1 control system, 1 HMI and 1 operator.

6. Safe filling nozzle: No solution overflows, no particles generation.

7. Auto faulty rejection system detected by the machine.

8. Production line length is reduced by 1/3, both workshop and air conditioning and cleaning area are reduced by 1/3, greatly reducing the initial investment and future running cost.

9. Simple structure, more stable and reliable performance.

 

 

 

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Dextrose Injection - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

Dextrose injection basically is manufactured from the homogeneous solution of dextrose and sterilized water. As raw material, there is abundant availability of dextrose in India. Basic plant and machinery?s as well as good fabricators also are fully available in India. The demand growth of this product is very appreciable. Right now it is increasing at a rate 5 % per annum. Few organized sector are engaged in the production of dextrose. But the demand is gradually increasing. So to meet the gap of demand and production, there require more production units. So this sector may be prospectus one for new entrepreneur. As a whole, this is a good one and one may be successful in this arena.
Plant capacity: 10000 Bottles/DayPlant & machinery: Rs. 82 Lakhs
Working capital: Rs. 151 LakhsT.C.I: Rs. 290 Lakhs
Return: 28.26%Break even: N/A
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Liquid Glucose From Maize - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

The maize also called “corn or Indian corn” is widely cultivated in India. Maize ranks high among the four or five principal cereal crops of the world. Maize is utilized in more diversified ways than any other cereal. The grain is quite nutritious, with a high percentage of easily digested carbohydrates, fats and proteins hardly and deleterious substances. Glucose is the form of white crystalline powder. Liquid Glucose or Glucose Syrup is a refined and concentrated non-crystallisable aqueous solution of d-glucose, maltose and other polymers of d-glucose, obtained by controlled hydrolysis of starch containing material. Glucose syrup is used in hard boiled sweets and many dairy products, as a granulating agent for tablet coating and as a vehicle for orally administered medical syrups in pharmaceuticals. It is used in the manufacture of canned food, bakery products, ice-creams, chewing tobacco, shoe polish and leather chemicals. There are various products from maize like maize starch and its by products and direct product of liquid glucose and dextrose from starch. It has good scope in the market.
Plant capacity: 500 tons/AnnumPlant & machinery: 20 Lakhs
Working capital: -T.C.I: 52 Lakhs
Return: 37.00%Break even: 53.00%
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LIQUID GLUCOSE FROM RICE - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

Rice is basically sources of starch content little amount of fat and protein in it. It contains also vitamins and minerals. Basic raw materials required for the production of liquid glucose are rice grains, enzymes, sulfuric acid etc. which are largely available in India. Glucose syrup is used in hard boiled sweets and many dairy products. It is used in the manufacture of canned foods, confectionery, bakery products, ice creams, chewing tobacco, shoe polish and leather chemicals. Market demand of liquid glucose is gradually increase according to increase of food market. As a whole it can be concluded that it is a feasible project. Any entrepreneur may go into the process, will be successful in this project.
Plant capacity: 30000 MT/AnnumPlant & machinery: 664 Lakhs
Working capital: -T.C.I: Cost of Project 1107 Lakhs
Return: 40.00%Break even: 50.00%
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DEXTROSE SALINE - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Layout

capacity (per day): 5000 Bottles of 5% Dextrose Saline 1000 Bottles of 10% Dextrose Saline 1000 Bottles of 25% Dextrose
Plant capacity: -Plant & machinery: Rs. 32 Lakhs
Working capital: -T.C.I: Rs. 180 Lakhs
Return: 57.00%Break even: 29.00%
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I.V. Fluid (International Standard) - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities

Infusion therapy as a basic toll of modern medical care enables the physician to restore and stabilize homeostasis states quickly and completely. In nursing homes and hospital where patients are suffering from acute dehydration or considerable debilitating conditions, the intra venous fluids are used as I.V. drips. The basic function of I.V. fluids is to replenish the body fluids. Although there are number of I.V. fluids, but generally three types of I.V. fluids are used in hospitals as I.V. drips. 1. Dextrose injection fluid. 2. Dextrose and sodium chloride injection fluid. 3. Sodium Chloride injection solution (Saline solution). Dextrose solution is used during postoperative period when sodium extraction of 10-15% are used as diuretic for increasing in urine flow. Saline solution is used when large amount of sodium has been lost by vomiting or by gastric or intestinal duodenal aspiration or through an alimentary fistula. Dextrose monohydrate is used as supplement to cows milk in part of feeding. Hypertonic dextrose solution (25-50%) is in medical treatment partly because they are believed to strengthen heart muscles. Hypertonic solutions are used in intravenous injection to relieve intractable pressure in-patient with hydrocephalus and meningitis. The drug industry has now achieved an impressive growth during the last four decades of planning and development. These I.V. fluids are the best alternative, which can yield sudden result in the health of a Patient by replenishing the body fluids.
Plant capacity: 30000 Bottles/DayPlant & machinery: Rs. 125 Lakhs
Working capital: -T.C.I: Rs. 816 Lakhs
Return: 65.00%Break even: 42.00%
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I V Fluid - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Economics

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Plant capacity: 30000 Bottles/Day, each Bottles 0.5 ltrs. capacityPlant & machinery: -
Working capital: -T.C.I: -
Return: 49.00%Break even: 40.00%
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MAIZE STARCH & LIQUID GLUCOSE - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

Maize starch is the most commonly used carbohydrate found in plants. Industrially, starch is classified into two types viz. natural & modified starch. It has many industrial applications, varying from the pulp and paper industry to the food industry. In fact, it is used as a thickener in improving the texture of many foods and can be used as a thickening agent for sauces, gravies, puddings and pie fillings. Raw starch is widely used as adhesive in corrugated & laminated paper boards. India is one of the major producers of maize in the world. It is grown in Uttar Pradesh, Bihar, Rajasthan, Punjab, Madhya Pradesh, Himachal Pradesh, Gujarat, Jammu & Kashmir, Andhra Pradesh, Mysore and Haryana. Liquid glucose is mostly used in the confectionery industry. It is also used in other firms, ranging from leather to textile industries. The principle raw material required is starch and mineral acid plus amylolytic enzymes. The domestic demand is 4000 M.T. per annum, which clearly indicates that there is a high demand of maize starch and liquid glucose. A new entrepreneur can well venture into this field since the biggest end user is pharmaceuticals.
Plant capacity: 61.56 MT/Day (Maize Starch), 50 MT /Day (Liquid Glucose) Plant & machinery: 2 Crores
Working capital: -T.C.I: 20 Crores
Return: 47.00%Break even: 28.00%
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STARCH AND ALLIED PRODUCTS FROM MAIZE(Starch, Liquid Glucose, Dextrose Monohydrate, Dextrose Anhydrous, Sorbitol and Vitamin C)- Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Plant Layout

Starch is a group of polysaccharides, composed of glucopyranose units joined together by-glucosidric linkages. It conforms to the molecular formula, (C6-H10O5)n, where n varies from a few hundred to over one million. Starch is found as the reserve carbohydrate in various parts of plants and is enzymatically broken down to glucose to other carbohydrates according to the metabolic needs of the plants. Industrially, starch is broadly divided into two types viz., natural and modified. Natural starches also designated as unmodified starches or simply starches are obtained from grains such as sorghum. From roots like potato, tapioca and arrowroot, and from the pith of the stems of certain palms such as sago. They are further classified into cereal starches and root starches. The characteristics of the natural starches are changed by chemical or enzymatic action and the products of these reactions are termed modified starches. This group includes dextrin, acid-modified starches, oxidized starches, starch esters, starch ethers, dialdehyde starches, and cationic starches. Starch can be obtained from maize, sorghum, roots and tubers such as tapioca, arrowroot, potato and from the pith of the stems of certain palms such as sago. Physical and chemical properties of starch vary according to the raw material from which it is derived. Starch is a high polymeric carbohydrate with the molecular formula (C6H10O5)n where n varies from a few hundred to over one granules, usually made up of both a linear polymer (amylose) and a branched polymer dissolves in hot water. Starch granules gelatinize in water when the temperature is raised to about 60-700C. At higher temperatures they well progressively to form a paste or solution and the shorter, linear molecules dissolve. The solutions form a gel on cooling depending upon the variety and concentration of starch present. Starch is an absorbent for water. Under normal atmospheric conditions most starches contain 10-17% moisture. Starch and Glucose are reserved carbohydrates of plants and are therefore widely distributed in their crude form. They can be found in almost all fruits, vegetables and corns. There is no definite information as to how they were initially obtained. But different countries are known to be using different agricultural sources for production of starch. While Japan and the European countries produce starch from potatoes, America from corn, countries like Thailand and Brazil are understood to be producing starch mainly from tapioca. In the case of India, starch is being produced from Maize as well as tapioca. While the units producing starch from maize are concentrated in large sector, the units producing starch from tapioca are large concentrated in the small-scale sector. Commercially glucose is produced from starch only and these two products are generally made in the same unit side by side. The history of starch and glucose Industry dates back to early forties before the Second World War starch used to be imported from European countries. But owing to difficulties in importing starch and difficulties in continuing the production of cotton textiles (where starch finds its extensive use in the manufacture of adhesives, sizing and finishing in textiles) two units namely Anil starch products with their factories located at Ahmedabad, in the year 1939 and 1941 respectively. Starch and Glucose can be used in different end use industries such as in the manufacture of adhesives, sizing and finishing in textiles, thickening agents in gravies, custards, and confectioneries. Sizing papers, Cosmetics, explosives, reagent, face powders, indicators in domestic analysis, water soluble packaging films, book bindings fabrics, distilled liquors, malt sugar, cattle feed ingredient, rubber reinforcing resins etc.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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SORBITOL, MALTITOL, DEXTROSE ANHYDROUS AND VITAMIN-C - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Production Schedule

Sorbitol is a water soluble polyhydric alcohol, having sweet taste and high stability besides properties of humectancy and plastisizing used in manufacture of tooth paste, tonics, pharmaceutical formulations, cosmetics etc. Maltitol is a polyol or sugar substitute that is understood to be almost as sweet as conventional granulated sugar. It is a reduced caloric bulk sweetener with sugar like taste and sweetness. Maltitol is especially useful in the production of sweets, sugarless hard candies, chewing gum, chocolates, baked goods and ice cream. It is useful in the diets of people with diabetes control of blood glucose. Lipids and weight are the three major goals of diabetes management today. Dextrose anhydrous is the purest form of dextrose, commonly called glucose. It is used in tableting (salt tablets) and as a raw material in the fermentation industry for biochemical synthesis of antibiotics and vitamin C, via sorbitol. Vitamin C, is a sugar acid and act as an antioxidant. This material is generally found in crystallized or powder form with white or light yellow appearance and is water soluble. Demand growth of this industry is very good. So there is good scope for new entrepreneurs. Few Indian major players are: (Sorbitol) Amaravati Chemicals Ltd. Gayatri Bioorganics Ltd. Gulshan Polyols Ltd. Hico Products Ltd. Jayant Vitamins Ltd. Sayaji Industries Ltd. Sukhjit Starch & Chemicals Ltd. Tan India Ltd. Unicorn Organics Ltd. (Dextrose) Indian Maize & Chemicals Ltd. Kamala Sugar Mills Ltd. Origin Agrostar Ltd. Tirupati Starch & Chemicals Ltd. Unique Sugars Ltd.
Plant capacity: 35 MT/Day, 15 MT Sorbitol, 5 MT Maltitol, 10 MT Dextrose Anhydrous, 5 MT/Day Vitamin C Plant & machinery: 607 Lakhs
Working capital: -T.C.I: 2332 Lakhs
Return: 39.00%Break even: 39.00%
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I.V. CANNULA (Intravenous Cannula) AND BUTTERFLY NEEDLES - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Cost of Project

A Cannula is a tube that can be inserted into the body, often for the delivery or removal of fluid. An intravenous cannula is a flexible tube which when inserted into the body is used either to withdraw fluid or insert medication. Cannula normally comes with a trocar attached which allows puncture of the body to get into the intended spaces. An intravenous (I.V.) cannula is inserted a vein, primarily for the administration of intravenous fluids, obtaining blood samples and administering medicines. An arterial cannula is inserted into an artery, commonly the radial artery, and used during major operation and in critical care areas to measure beat-to-beat blood pressure. The cannula is also used in an emergency procedure to relieve pressure and bloating in cattle due most commonly to their accidentally grazing wilted legume or legume-dominant pastures. They are also a component used in the insertion of the verichip. A butterfly needle or casually a butterfly is named because of the plastic handles attached to the needle resemble butterfly wings. The butterfly needle may have a smaller diameter needle than the usual blood drawing needle, but not necessarily. It is sometimes less awkward for the blood drawer to have the flexible tubing separating the syringe. They are useful in difficult venepuncture because the handles allow much finer control of the needles. They can also be useful for a one off administration of intravenous drugs. The demand of I.V. Cannula and Butterfly needles is increasing rapidly, so there is wide scope for new entrepreneurs.
Plant capacity: Total 60,000 Pcs/Day, 30,000 Pcs./Day (I.V. Cannula), 30,000 Pcs./Day (Butterfly Needles)Plant & machinery: 191 Lakhs
Working capital: -T.C.I: 539 Lakhs
Return: 42.00%Break even: 43.00%
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Information
  • One Lac / Lakh / Lakhs is equivalent to one hundred thousand (100,000)
  • One Crore is equivalent to ten million (10,000,000)
  • T.C.I is Total Capital Investment
  • We can modify the project capacity and project cost as per your requirement.
  • We can also prepare project report on any subject as per your requirement.
  • Caution: The project's cost, capacity and return are subject to change without any notice. Future projects may have different values of project cost, capacity or return.

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