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Active Pharma Ingredients (API) - Global Market Estimated to Reach US$ 21.9 billion by 2023: Investment Opportunity for Startups and Entrepreneurs, Medications, Drugs and Pharmaceuticals, Cephalexin Monohydrate, Ampicilin Trihydrate, Ibuprofen

Monday, September 19, 2016

Active Pharma Ingredients (API) - Global Market Estimated to Reach US$ 21.9 billion by 2023: Investment Opportunity for Startups and Entrepreneurs, Medications, Drugs and Pharmaceuticals, Cephalexin Monohydrate, Ampicilin Trihydrate, Ibuprofen Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Economics, Production Schedule, Working Capital Requirement, Plant Layout, Process Flow Sheet, Cost of Project, Projected Balance Sheets, Profitability Ratios, Break Even Analysis

 

Active Pharmaceutical Ingredients are portions of any drug, which are active. Thus, depending on the drug’s administered dosage, the reactions and results differ. Certain drugs are comprised of more than one kind of API. APIs of good quality are essential for the manufacture of effective and safe medicines. Manufacturers use certain standards to determine how strong the API is in each drug. However, the standard can vary widely from one brand to another. One brand might use one test, another a different one.

On the basis of type of manufacturers of active pharmaceutical ingredient, the market can be categorized as in-house active pharmaceutical ingredient manufacturing and active pharmaceutical contract manufacturing. The in-house active pharmaceutical ingredient manufacturing leads the active pharmaceutical ingredient market by type of manufacturer category. In addition, the in-house manufacturing is continuously witnessing decline in the segment due to reduced profitability and high research and development cost. On the basis of type of active pharmaceutical ingredient, the market can be categorized as biological active pharmaceutical ingredients, and synthetic chemical active pharmaceutical ingredients.

An active ingredient (AI) is the substance in a pharmaceutical drug or a pesticide that is biologically active. The similar terms active pharmaceutical ingredient (API) and bulk active are also used in medicine, and the term active substance may be used for pesticide formulations. Some medications and pesticide products may contain more than one active ingredient. A dosage form: the API, which is the drug itself; and an excipient, which is the substance of the tablet, or the liquid the API is suspended in, or other material that is pharmaceutically inert. Drugs are chosen primarily for their active ingredients. The Indian pharmaceutical industry also needs to take advantage of the recent advances in biotechnology and information technology. The future of the industry will be determined by how well it markets its products to several regions and distributes risks, its forward and backward integration capabilities, its R&D, its consolidation through mergers and acquisitions, co-marketing and licensing agreements.

 

Uses and Applications

API like Cephalexin is used to treat a number of infections including: otitis media, streptococcal pharyngitis, bone and joint infections, pneumonia, cellulitis, and urinary tract infections. It may be used to prevent bacterial endocarditis. Amoxicillin is used in the treatment of a number of infections, including acute otitis media, Streptococcal pharyngitis, pneumonia, skin infections, urinary-tract infections, Salmonella, lyme disease, and chlamydia infections. It is also used to prevent bacterial endocarditis in high-risk people who are having dental work done, to prevent strep pneumococus infections in those without spleens, and for both the prevention and the treatment of anthrax. Ibuprofen is used primarily for fever, pain, dysmenorrhea and inflammatory diseases such asrheumatoid arthritis. It is also used for pericarditis and patent ductus arteriosus.

 

Market Survey

The demand for pharmaceutical products in India is significant and is driven by low drug penetration, rising middle-class & disposable income, increased government & private spending on healthcare infrastructure, increasing medical insurance penetration etc. India based pharmaceutical companies are not only catering to the domestic market and fulfilling the country’s demands, they are also exporting to around 220 countries. They are exporting high quality, low cost drugs to countries such as the US, Kenya, Malaysia, Nigeria, Russia, Singapore, South Africa, Ukraine, Vietnam, and more.

India has the world's third largest active pharmaceutical ingredients (API) for the industry valued at a little less than USD 2 bn. Top 5 API producers account for approximately 6.5 %.The growth has been driven by many factors, such as legislative reforms, growth in contract manufacturing and outsourcing, value added foreign acquisitions and joint ventures and India's acu-men and expertise in reverse engineering of patented drug molecules. India has, in the meantime,  been trying to comply with the World Trade Organization's Trade Related Intellectual Property Agreement (TRIPs) obligations.

Production of active pharmaceutical ingredients is a highly sophisticated and technically demanding process. The global active pharmaceutical ingredient market is surging due to the increased demand for pharmaceutical drugs, which in turn is driven by aging population, increasing prevalence of chronic diseases such as cancer, diabetes, cardiovascular, neurological and infectious diseases among others. The global Active Pharmaceutical Ingredient market for was valued at US$ 12.9 bn in 2014 and is estimated to reach US$ 21.9 billion by 2023 at a CAGR of 6.3% from 2015 to 2023.

Few Major Players are as under:-

Cipla          

Ranbaxy Lab                  

Dr Reddy's Labs             

Sun Pharma         

Lupin Ltd             

Aurobindo Pharma          

Piramal Health     

Cadila Health       

Matrix Labs

Wockhardt 

 

Table of Contents

 

1.       Project Location

1.1.    City Profile & Geotechnical Site Characterization

1.1.1.General

1.1.2.Physical Characteristics

1.1.3.Map

1.1.4.Languages and Culture

1.1.5.Climate &Rainfall

1.1.6.Transportation and Communications

1.1.7.Economy & Industry

2.       Introduction

2.1.    Steps to Strengthen the Industry

3.       Cefalexin Monohydrate

3.1.    Introduction

3.2.    Uses

3.2.1.Infections

3.2.2.Formulations

3.3.    Raw Material

3.4.    Manufacturing Process

3.5.    Process Flow Diagram

4.       Ampicillin Trihydrate

4.1.    Introduction

4.2.    Uses

4.2.1.Chemical Data

4.3.    Raw Material

4.4.    Manufacturing Process

4.5.    Process Flow Diagram

5.       Ibuprofen

5.1.    Introduction

5.2.    Uses

5.3.    Chemistry

5.4.    Raw Material

5.5.    Manufacturing Process

5.6.    Process Flow Diagram

6.       Market Survey

6.1.    Current Scenario

6.2.    Major Pharmaceutical Companies

6.3.    Government Initiatives

7.       Financials & Comparison of Major Indian Players/Companies

7.1.    About Financial Statements of CMIE Database

7.2.    Profits & Appropriations

7.3.    Total Liabilities

7.4.    Total Assets

7.5.    Net Cash Flow from Operating Activities

7.6.    Section – I

7.6.1.Name of Company with Contact Details

7.6.2.Name of Director(S)

7.6.3.Plant Capacity

7.6.4.Location of Plant

7.6.5.Capital Expenditure Projects

7.6.6.Name of Raw Material(S) Consumed with Quantity & Cost

7.7.    Section – II

7.7.1.Assets

7.7.2.Cash Flow

7.7.3.Cost as % ge of Sales

7.7.4.Forex Transaction

7.7.5.Growth in Assets & Liabilities

7.7.6.Growth in Income & Expenditure

7.7.7.Income & Expenditure

7.7.8.Liabilities

7.7.9.Liquidity Ratios

7.7.10.    Profitability Ratio

7.7.11.    Profits

7.7.12.    Return Ratios

7.7.13.    Structure of Assets & Liabilities (%)

7.7.14.    Working Capital & Turnover Ratios

8.       Export &Import Statistics Data of India

8.1.    Export Statistics Data Cefalexin

8.2.    Import Statistics Data Cefalexin

8.3.    Export Statistics Data Cefalexin Trihydrate

8.4.    Import Statistics Data Ampicillin Trihydrate

8.5.    Export Statistics Data Ibuprofen

8.6.    Import Statistics Data Ibuprofen

9.       Present Manufacturers

10.   List of Pharmaceutical Companies in India

11.   Buyer’s List

11.1.1.    Contact Details of Buyer’s

11.1.2.    Name of Director(S)

11.1.3.    Plant Capacity

11.1.4.    Location of Plant

11.1.5.    Name of Raw Material(S) Consumed with Quantity & Cost

12.   Suppliers of Plant & Machinery

13.   Suppliers of Raw Material

14.   Product & Machinery Photographs

14.1.Product Photographs

14.2.Machinery Photographs

15.   Plant Layout

 

PROJECT FINANCIALS

·         Project at a Glance

Annexure

·         Assumptions for Profitability workings ….…………………………………………....................... 1

·         Plant Economics…………………………………………………………………………….................... 2

·         Production Schedule……………………………………………………………………….................... 3

·         Land & Building…………………………………………………………………………….................... 4

§  Factory Land & Building

§  Site Development Expenses

·         Plant & Machinery………………………………………………………………………….................... 5

§  Indigenous Machineries

§  Other Machineries (Miscellaneous, Laboratory etc.)

·         Other Fixed Assets………………………………………………………………………….................... 6

§  Furniture & Fixtures

§  Pre-operative and Preliminary Expenses

§  Technical Knowhow

§  Provision of Contingencies

·         Working Capital Requirement Per Month………………………………………………................. 7

§  Raw Material

§  Packing Material

§  Lab & ETP Chemical Cost

§  Consumable Store

·         Overheads Required Per Month and Per Annum ……………………………………................. .8

§  Utilities & Overheads (Power, Water and Fuel Expenses etc.)

§  Royalty and Other Charges

§  Selling and Distribution Expenses

·         Salary and Wages ……………………………………………………………………………................. 9

·         Turnover Per Annum ………………………………………………………………………................ 10

·         Share Capital…………………………………………………………………………………................ 11

§  Equity Capital

§  Preference Share Capital

 

 

•        Annexure 1            ::        Cost of Project and Means of Finance

•        Annexure 2            ::        Profitability and Net Cash Accruals

§  Revenue/Income/Realisation

§  Expenses/Cost of Products/Services/Items

§  Gross Profit

§  Financial Charges    

§  Total Cost of Sales

§  Net Profit After Taxes

§  Net Cash Accruals

 

•        Annexure 3            ::        Assessment of Working Capital requirements

§  Current Assets

§  Gross Working Capital

§  Current Liabilities

§  Net Working Capital

§  Working Note for Calculation of Work-in-process

 

•        Annexure 4            ::        Sources and Disposition of Funds

•        Annexure 5            ::        Projected Balance Sheets

§  ROI (Average of Fixed Assets)

§  RONW (Average of Share Capital)

§  ROI (Average of Total Assets)

 

•        Annexure 6            ::        Profitability ratios

§  D.S.C.R

§  Earnings Per Share (EPS)

§  Debt Equity Ratio

 

•        Annexure 7            ::        Break-Even Analysis

§  Variable Cost & Expenses

§  Semi-Variable/Semi-Fixed Expenses

§  Profit Volume Ratio (PVR)

§  Fixed Expenses / Cost 

§  B.E.P

 

•        Annexure 8 to 11   ::        Sensitivity Analysis-Price/Volume

§  Resultant N.P.B.T

§  Resultant D.S.C.R

§  Resultant PV Ratio

§  Resultant DER

§  Resultant ROI

§  Resultant BEP

 

•        Annexure 12          ::        Shareholding Pattern and Stake Status

§  Equity Capital

§  Preference Share Capital

 

•        Annexure 13          ::        Quantitative Details-Output/Sales/Stocks

§  Determined Capacity P.A of Products/Services

§  Achievable Efficiency/Yield % of Products/Services/Items 

§  Net Usable Load/Capacity of Products/Services/Items   

§  Expected Sales/ Revenue/ Income of Products/ Services/ Items   

 

•        Annexure 14          ::        Product wise domestic Sales Realisation

•        Annexure 15          ::        Total Raw Material Cost

•        Annexure 16          ::        Raw Material Cost per unit

•        Annexure 17          ::        Total Lab & ETP Chemical Cost

•        Annexure 18          ::        Consumables, Store etc.

•        Annexure 19          ::        Packing Material Cost

•        Annexure 20          ::        Packing Material Cost Per Unit

•        Annexure 21          ::        Employees Expenses

•        Annexure 22          ::        Fuel Expenses

•        Annexure 23          ::        Power/Electricity Expenses

•        Annexure 24          ::        Royalty & Other Charges

•        Annexure 25          ::        Repairs & Maintenance Expenses

•        Annexure 26          ::        Other Manufacturing Expenses

•        Annexure 27          ::        Administration Expenses

•        Annexure 28          ::        Selling Expenses

•        Annexure 29          ::        Depreciation Charges – as per Books (Total)

•        Annexure 30          ::        Depreciation Charges – as per Books (P & M)

•        Annexure 31          ::        Depreciation Charges - as per IT Act WDV (Total)

•        Annexure 32          ::        Depreciation Charges - as per IT Act WDV (P & M)

•        Annexure 33          ::        Interest and Repayment - Term Loans

•        Annexure 34          ::        Tax on Profits

•        Annexure 35          ::        Projected Pay-Back Period And IRR

 

 

See more

https://goo.gl/dwgi0H

https://goo.gl/qRJmnp

https://goo.gl/t2QFiI

 

Contact us:

Niir Project Consultancy Services

106-E, Kamla Nagar, Opp. Spark Mall,

New Delhi-110007, India.

Email: [email protected], [email protected]ia.co

Tel: +91-11-23843955, 23845654, 23845886, 8800733955

Mobile: +91-9811043595

Fax: +91-11-23841561

Website :

http://www.niir.org

http://www.entrepreneurindia.co

Source: NPCS Team


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