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Pharmaceutical, Drugs, Fine Chemicals, Bulk Drug Intermediates, Pharmaceutical Drugs, Pharma Drug Ingredients Intermediates, Drug Intermediates, Speciality Chemicals, Raw Materials, Fine and Specialty Chemicals Intermediates, Pharmaceutical Bulk Drugs

Indian drugs and pharmaceutical industry has advanced perceptibly and is getting ready  for the new patent regime and  to withstand global competition, which is expected to be unleashed by new winds of liberalisation - a new era of liberalisation - much different from what was ushered in since the conclusion of the Uruguay Round and the establishment of the World Trade Organisation.

The industry has been expanding at annual rates ranging between 8 to 10% (against global growth rate of 6%).  According to a study  by McKinsey, Vision 2010, the domestic pharmaceutical industry could attain a size of  $25 billion (Rs 1200 billion) by 2010 by focusing on two areas: first, innovation-led research, development and new drug discoveries; and second, information technology-led remote sales and marketing.  The market for bulk drugs and formulations had increased from about Rs 103  billion in 1990-91 to an estimated Rs 435  billion at the end of 2003-04.  The prices of Indian essential drugs are among the lowest in the world. Apart from strides made by the industry in the last half-a-century, lower production cost due to reverse engineering and low R&D outlays has been a major factor in keeping the prices under check.

The global pharmaceutical industry is estimated at $ 300 billion, not all representing cross-border trade.  India's measly share of $ 1.5 billion in global trade represents an untapped potential. Under the regime of economic liberalisation underway since early 1990s, the drugs and pharmaceutical sector witnessed initiatives at fresh investment in the sector. Nearly 1735 investment proposals of the order of around Rs 166  billion were initiated. The foreign collaboration proposals approved numbered around 425 with a foreign direct investment  (FDI) component of over Rs 25 billion. The pharmaceuticals have figured high on the export front. In 2001-02,  the sector was  estimated to have registered a growth of 17.6% at around Rs 20.3 billion.

In the wake of economic liberalisation, many a  overseas players  returned or contemplated returning to India. These include Ivox Corp (USA),  Taro Pharmaceuticals (Israel) and Merck (USA). These are out either to set shop or looking for acquisitions in India. Hexal AG of Germany has established a liaison office in India. MILLIONCs like Rocha, Bayer, Aventis and Chiron are making India a regional hub for bulk drugs. 

The Export Import Bank of India (Exim Bank) had  doubled its corpus for the pharmaceutical industry to Rs 2 billion as a result of increased activity in the industry, especially in the external sector. The fund is used for the development and commercialisation of the new products and applications, significant improvement in the existing design of  products, setting up and expansion of pilot plants, research studies for obtaining regulatory approvals, cost of filing and managing international patent and R&D Centres.

It needs, however, to be recognised that the presence  of small scale manufacturers has resulted, on the one hand,  in a highly fragmented industry, and on the other, it has made it possible to supply a near 100,000 drugs including vitamins, antibiotics, antibacterials, cardio-vascular and other essential drugs. These account for nearly 37% of the market.  While each of about 80% of the manufacturers has annual sales below a billion rupees, top ten companies are known to control over 30% of the market. At present there are more than 20,000 players in the country.

The major players are: Alembic Chem, Aurobindo Pharma, Cipla, Dr. Reddy's, FDC, IPCA Labs, Jagsonpal Pharma, J.B. Chemicals, Kopran, Lupin Labs, Lyka Labs, Morepan Labs, Nicholas Piramal, Ranbaxy Labs, Sun Pharma, Themis Medicare, GlaxoSmithkline, Astrazeneca, Aventis, E-Merck, Torrent Pharma, TTK Healthcare, Unichem Labs,  Wockhardt  and  Zandu Pharma.  Until recently, only a few of the Indian companies had gone into any serious R&D activity. Much of the effort was directed to affordable analogue research. The R&D level in the country is low with even well-placed pharma companies spending less than 2% of turnover on R&D. MILLIONCs are known to contribute as much as 10% or more of their turnover to R&D.  While India is very strong in process chemistry, biology and applied bio-chemistry, initiatives at all levels - government, academia, private sector - involving heavy financial outlays, are called for.

Ayurveda continues to remain a preferred system of medicine for a vast segment of population in the country. The country has over 400,000 registered practitioners of the Indian system of medicine. Around 170 institutes properly affiliated to various universities impart under- or post-graduate courses each year. These institutes churn out some 5,500 fresh practitioners. The practitioners are supported by 12,000 dispensaries and 2,100 beds available for ayurveda treatment countrywide. The emerging biotechnology sector has already taken by storm and is offering sops to states to make these as the thriving ground for the highly potential segment in medicare.

How to Prepare Project Report on Pharmaceutical Processing Industry?

Drug manufacturing companies work under strict laws and regulations. Their processes need to comply with relevant drugs act in their respective countries.

Therefore, if you are planning to invest in pharmaceutical processing, a good project report will be necessary. Besides the prominent aspects of a project report, you should pay close attention to the following issues in a pharmaceutical processing report.

1. Marketing

This industry is very competitive. I need not stress the value of detailed market analysis. You need to understand the status of market competition and the demand for pharmaceutical products. A proper market analysis will additionally help you prepare an excellent pharmaceutical business plan. Given your market analysis report, you will develop a marketing plan.

2. Government approval

In almost all countries, there are laws and regulations for the manufacture, distribution, and administration of drugs. Consider giving a status report on these requirements when making the final project status report.

3. Manufacturing Process

It would help if you had a picture of the process you will employ in making your drugs. Outline the quality checks and balances in the process. State the required pharmaceutical intermediates and their corresponding active pharmaceutical ingredients.

4. Machines and Equipment

You need to identify the equipment you will need, such as homogenizers, spectrophotometer, tabulating machines, etc. to ensure the machines meet quality specifications. You may also need to put down a plan to train workers on their operations.

How Does the Drug Manufacturing Process Work?

If you are an aspiring drug manufacturer, you should know how the bulk drug manufacturing process works. This is a complicated process and requires professional skills in molecular biology, medical microbiology, and pharmacy.

The process involves four steps, namely:

  • Milling
  • Granulation
  • Coating
  • Tabulation

Milling is important because it makes the drug powder uniform. It ensures uniform distribution of the active pharmaceutical ingredients. Additionally, milling makes it easier to formulate the drug into a syrup or emulsion.

After milling, you can use wet or dry granulation to form granules. You then coat them and compress the drugs using a tabulating machine. Alternatively, you can fill the granules into capsules.

For any chemical industry business ideas, prioritize the security of your staff. Ensure workers have sufficient PPEs. Have plans to protect them from chemical poisoning. Install eyewashes and emergency showers in both production units and laboratories.

Pre-Feasibility Report on Bulk Drug Manufacturing Process

Before you set up a feasibility report or start making a business plan, you first need to do a pre-feasibility study. It is the conclusions of this study that will make you decide whether to proceed to the project feasibility report or not.

Implementing a pharmacy business plan is an expensive affair. Please do not put any investment into a business plan of this magnitude without looking at its feasibility study report.

Considering the variety of pharmaceutical products, a feasibility plan will help you decide on the most relevant product for your target market. The results of pre-feasibility and feasibility studies will inform your marketing strategy plan. At the pre-feasibility stage, you get to review the technical skills required for the bulk drug manufacturing process. You also assess the knowledge level and determine whether you have the knowledge and skills.

Lastly, this report looks at the financial demands of a chemical project report on bulk drug processing. From here, you will decide on the feasibility of the project.

How to Grow Pharmaceutical Intermediates Market?

The pharmaceutical industry relies on pharmaceutical intermediates. We use these chemicals to produce active pharmaceutical ingredients (API). 

To grow the pharmaceutical intermediates market, therefore, we should focus on the drug manufacturing industry. Here are some tips on how we can grow this industry.

1. Investment in Research and Development

We should encourage governments and established drug manufacturers to invest in research and development of new medicines. New drug development will increase the need for pharmaceutical intermediates. Consequently, this will cause the growth of the industry.

2. Boost Generic Drug Manufacturing

Feasibility study reports for project ideas in pharmaceuticals show a growing demand for generics. This demand is particularly high in developing countries. More investment in generic drugs will result in increased demand for pharmaceutical intermediates.

3. Collaborations

It is quite expensive to run a pharmaceutical intermediate processing company. If you look at a project summary example for the local industry and you will notice the huge investment. One way of cushioning the industry is to encourage collaborations, mergers, and acquisitions. Working together gives small-scale companies a competitive advantage. It lowers their operation costs and improves revenue.

How to Set Up a Chemical Industry Business Plan?

Writing a chemical industry business plan begins with a pre-feasibility study. Here, you look at the various business ideas in chemical manufacturing. You then evaluate each of these ideas based on:

1. Skills and Knowledge

If you are interested in the chemical manufacturing industry, I assume that you have some skills or knowledge in this sector. If so, look at the skills required for each idea you have. Which of these ideas marches your skills and knowledge?

2. Financial Resources

Different chemical processes have different cost implications. Try to review each idea against the expected financial input. You can examine some business plan examples on the internet to get a hint on required inputs. Once you have a convincing pre-feasibility report, you can proceed to make a feasibility report meaning the idea is profitable and viable.

The next step in setting up a chemical industry business plan is to prepare a small business marketing plan. The results of your feasibility report will help do this.

Chemical manufacturing is not only expensive, but it is also strictly regulated by law. It would be best if you had an innovative marketing strategy to break even. It would be best if you did an accurate market analysis.

A project report on the chemical industry helps you assess the dynamics of the industry. You will want to know who the major chemical manufacturers are. You will also assess the availability of raw materials and machinery for your chemical industry.

In your project report, you will also address the technical aspects of the chemical manufacturing process. You need to draw a flow diagram for the process. Lastly, sit down and draw a business plan for your chemical industry business. You will need the information from all the above processes. Additionally, a business plan will consider the financial implications of your chemical industry project report.

After reading the information above, I believe you can set up a feasible business plan for the chemical industry. You may need to consult an expert to help you with the finer details of a chemical industry business plan.

We can provide you detailed project reports on the following topics. Please select the projects of your interests.

Each detailed project reports cover all the aspects of business, from analysing the market, confirming availability of various necessities such as plant & machinery, raw materials to forecasting the financial requirements. The scope of the report includes assessing market potential, negotiating with collaborators, investment decision making, corporate diversification planning etc. in a very planned manner by formulating detailed manufacturing techniques and forecasting financial aspects by estimating the cost of raw material, formulating the cash flow statement, projecting the balance sheet etc.

We also offer self-contained Pre-Investment and Pre-Feasibility Studies, Market Surveys and Studies, Preparation of Techno-Economic Feasibility Reports, Identification and Selection of Plant and Machinery, Manufacturing Process and or Equipment required, General Guidance, Technical and Commercial Counseling for setting up new industrial projects on the following topics.

Many of the engineers, project consultant & industrial consultancy firms in India and worldwide use our project reports as one of the input in doing their analysis.

We can modify the project capacity and project cost as per your requirement.
We can also prepare project report on any subject as per your requirement.

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NICOTINE FROM TOBACCO WASTE - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

From harvesting of tobacco to manufacture of product large quantities of waste material comprising rejected leaves, broken bits of lamina, midribs stalks & stems accumulate. Such material, however, can be utilized with considerable benefit. In addition, many other chemicals like nicotinic acid, rutin, pectin and certain organic acids can be produced from these wastes. Nicotine is extensively employed as an agricultural insecticide as it is effective against a number of vegetable and fruit tree, particularly the soft bodies and minute insects. It also combats lice, gadflie, and flocks. Nicotine is also used in the manufacture of nicotine acid and nicotinamide, which are employed in the assessing supta-optico-hypophysical or peripheral sympathetic nerves functions. Nicotinamide is also used intravenously in the treatment of tuberculosis. Nicotine is also extensively used in medicines. It is also used in tanning industry. Nicotine is by far the most important by-product derived from tobacco waste. Nicotine is classed as a contact insecticide, but appears act to principally as fumigant and sometimes as a stomach poison. Nicotine is one of important alkaloid chemical having various applications. Its major use is found as insecticide for various fruits & vegetables. Now days, the nicotine is sold in the market as nicotine sulphate 40 % concentration. In agriculture it is used in the form of nicotine sulphate solution to control different pests and fungi in crops. Being a potential pesticide obtained from natural resources, it has a very good market potential in the agricultural sectors.
Plant capacity: 9,000 Ltrs./AnnumPlant & machinery: 43 Lakhs
Working capital: -T.C.I: 153 Lakhs
Return: 44.00%Break even: 47.00%
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Ciprofloxacin HCl –Cipro - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

PRODUCT PROFILE Ciprofloxacin belongs to a class of drugs called quinolone antibiotics. It is a second generation fluoroquinolone antibacterial. It works by stopping the growth of bacteria and kills bacteria by interfering with the enzymes that cause DNA to rewind after being copied, which stops synthesis of DNA and of protein. Ciprofloxacin interacts with other drugs, herbal and natural supplements, and thyroid medications. Ciprofloxacin was first patented in 1983 by Bayer A.G. and subsequently approved by the U.S. Food and Drug Administration (FDA) in 1987. Ciprofloxacin hydrochloride, USP, a fluoroquinolone, is the monohydrochloride monohydrate salt of 1 cyclopropyl 6 fluoro 1, 4 dihydro 4 oxo 7 (1 piperazinyl) 3 quinolinecarboxylic acid. Ciprofloxacin inhibits an enzyme called DNA gyrase that is an essential component of the mechanism that passes genetic information onto daighter cells when a cell divides. Product characteristics Trade names - Ciloxan, Cipro Mol. Formula. - C17H18FN3O3HCl.H2O Molecular weight - 385.8 Appearance - Powder; does not mix well with water. Description - Antibiotic Shelf life - Good Bioavailability - 69% State - Solid, Divided solid Applications Ciprofloxacin is used to treat a number of infections including: infections of bones and joints, endocarditis, gastroenteritis, malignant otitis externa, respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, chancroid, among others. Ciprofloxacin is available as tablets, intravenous solutions, eye and ear drops. It can also be used to treat some sexually transmitted infections (STIs), some forms of infectious diarrhea, and typhoid fever. The extended release form of ciprofloxacin is used to treat bladder and kidney infections. Global demand • India accounts for less than two per cent of the world market for pharmaceuticals, with an estimated market value of US$10.4 billion in 2007 at consumer prices, or around US$9 per capita. • Espicom's market projections put the market at US$15.6 billion by 2012 by assuming a modest but sustainable market growth of around 8.4% per year. • However, McKinsey has predicted that just the Indian domestic market alone is expected to grow from US$6.3 billion in 2005 to about US$20 billion by 2015. • The Indian pharmaceutical industry is the fourth largest in the world in terms of volume of output and thirteenth in domestic demand. However, the Indian industry, valued at USD 17 bn in represented just over 1% of the global pharmaceutical industry (USD 1700 bn) in value terms. The domestic market is estimated at Rs 680 bn. The demand of Ciprofloxacin in the market is immense and therefore its market position is splendid. Hence it is an excellent field to venture.
Plant capacity: 180 MT/ AnnumPlant & machinery: 225 Lakhs
Working capital: -T.C.I: Cost of project: 549 Lakhs
Return: 43.00%Break even: 59.00%
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MODIFIED POTATO STARCH - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

PRODUCT PROFILE Potato starch is starch extracted from potatoes. The cells of the root tubers of the potato plant contain starch grains (leucoplasts). To extract the starch, the potatoes are crushed; the starch grains are released from the destroyed cells. The starch is then washed out and dried to powder. Potato starch is essential as a universal binding and food thickening agent. Leveraging on potato starch production and producing modified potato starch that is specially customized for various applications in food, textile and paper manufacturing industries. Product characteristics Appearance - powder a clear white colour Surface of starch granules app. 30 ha/g Specific density app. 1.55 g/ml Specific heat 1.22 J/g Bulk weight of starch 80% DS app. 0.7 g/ml DS of moist centrifuge app. 0.6 g/ml Brightness (MgO2 = 100%) app. 95 % Size ranges between 5 and 100 ?m Applications Starch and modified starches have a broad range of applications both in the food and non food sectors. The largest users of starch in the EU (30%) are the paper, cardboard and corrugating industries. Other important fields of starch application are textiles, cosmetics, pharmaceuticals, construction and paints. In the medium and long run starch will play an increasing role in the field of “renewable raw materials” for the production of biodegradable plastics, packaging material and moulds. The powder has very consistent as the major raw materials are available in house with very good quality. The best value provided by the modified starch over native starch is the reduction in downtime and improvement in paper quality. Additional benefits offered by the modified starches are improvement in wastewater discharge quality with charged starches, elimination of chemical and equipment for on site conversion of native starches, reduction in labor costs due to the simplicity of cooking and using modified starches etc. Global demand Starch, one of the most present biomaterials has witnessed significant developments over the years. After witnessing a temporary dip in growth in the year 2008 and 2009, the world market for starch, by consumption is expected to recover and register healthy growth to reach 80 million metric ton by 2015. The Global starch market is likely to get respite from deceleration in its market growth, with growth poised to receive a new lease of life in the next few years, thanks to the growing consumption of liquid starches and modified starches. The modified starch market is projected to be the fastest growing segment over the period 2007-2015. The US represents the largest geographic market for starch, having accounted for a share of about 51% in the total volume of starch consumed in 2009. Given the countrys large per capita income, the demand for starch in the US has been steadily on the rise. Asia Pacific represents the fastest growing market over the period 2007-2015. Growing employment opportunities, and subsequent increase in per capita income over the last few years, particularly in China and India, have been driving the growing demand for starch in the region. The demand of the product in the market is immense and therefore its market position is splendid. Hence it is an excellent field to venture.
Plant capacity: 45000 MT/AnnumPlant & machinery: 654 Lakhs
Working capital: -T.C.I: Cost of the project: 1618 Lakhs
Return: 43.00%Break even: 50.00%
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VITAMIN C - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Economics

PRODUCT PROFILE Vitamin C is an essential nutrient for humans and certain other animal species. In living organisms ascorbate acts as an antioxidant by protecting the body against oxidative stress. It is also a cofactor in at least eight enzymatic reactions including several collagen synthesis reactions that, when dysfunctional, cause the most severe symptoms of scurvy. In animals these reactions are especially important in wound-healing and in preventing bleeding from capillaries. Vitamin C is a water soluble vitamin, meaning that your body does not store it. We have to get what we need from food, including citrus fruits, broccoli, and tomatoes. Low levels of vitamin C have been associated with a number of conditions, including high blood pressure, gallbladder disease, stroke, some cancers, and atherosclerosis, the buildup plaque in blood vessels that can lead to heart attack and stroke. Getting enough vitamin C from your diet by eating lots of fruit and vegetables may help reduce the risk of developing some of these conditions. Product characteristics • Alternate name - L-Ascorbic acid, L-3-Ketothreohexuronic acid lactone • Chemical formula - C6H8O6 • Molecular mass - 176 amu • Appearance - White mono clinic, crystalline solid • Odour - Odourless Source of Vitamin C: Most animals manufacture their own vitamin C. Primates, such as humans, gorillas, and monkeys, have somehow lost this ability, which is why we need to get our vitamin C from our diets. It is well known that citrus fruits, such as oranges, lemons, grapefruits, tangerines, limes, mandarins and others contain vitamin C. Other good sources are tomatoes, strawberries, raspberries, peppers, broccoli, asparagus, brussels sprouts, cauliflower, cabbage, peas, rutabagas, cantaloupe, kiwi, papayas, potatoes, paprika and watermelon. Many other fruits and vegetables contain small amounts of vitamin C, too. APPLICATIONS OF Vitamin C: • Vitamin C is used as an anti scorbutic and is used in the prevention and treatment of scurvy. • It is used in the treatment of hay fever, for relief of heat cramps and in the treatment of idiopathic methemoglobinemia. • Vitamin C is used in the manufacture of various anti tussive syrups such as neogadine exlixir, sanvitone, autrin etc. • It is a co enzyme in the synthesis of phenyl alanine and tyrosine in the human body. • Because vitamin C is a biological reducing agent, it is also linked to prevention of degenerative diseases such as cataracts, certain cancers and cardiovascular diseases. • Vitamin C plays a significant role in metabolic synthesis cortical hormones. • Vitamin C is needed for healthy gums, to help protect against infection, and assisting with clearing up infections and is thought to enhance the immune system and help reduce cholesterol levels, high blood pressure and preventing arteriosclerosis. • In food industry, vitamin C has a dual role: it acts as a nutrient as well as a food anti oxidant and product improver. • It protects and strengthens skin tissues and cells against external attacking factors such as oxidation damage resulting from attack of free radical and oxygen-derived, ultra violet radiation, pollutants etc. GLOBAL SCENARIO: The demand for Vitamin C is likely to go up steadily in the coming years, in view of the expected growth of the healthcare facilities in India. World production of synthesized vitamin C is currently estimated at approximately 110,000 tonnes annually. Global demand for vitamin C for the period of 2010 is around 120,000 tonnes, global sales of Vitamin C is over US$1020 million and growth rate in demand for Vitamin C is 3% per annum. Vitamin C represents more than 50% of the total production and sales of vitamins in the global market. China holds around 80% of world production of vitamin C. China plays a monopoly in the production of Vitamin C
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 1.00%Break even: N/A
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I V (Intravenous)Fluid (FFS Technology)

Profile Intravenous fluids are fluids which are intended to be administered to a patient intravenously, directly through the circulatory system. These fluids must be sterile to protect patients from injury, and there are a number of different types available for use. Many companies manufacture packaged intravenous fluids, as well as products which can be mixed with sterile water to prepare a solution for intravenous administration. Intravenous fluids can be broken into two broad groups. Crystalloids such as saline solutions contain a solution of molecules which can dissolve in water. When crystalloids are administered, they tend to create low osmotic pressure, allowing fluid to move across the blood vessels, and this can be linked with edema. Colloids contain particles which are not soluble in water, and they create high osmotic pressure, attracting fluid into the blood vessels. Blood is an example of a commonly administered intravenous colloid. Application Intravenous fluids can also be used as a route of medication administration. If a doctor wants to deliver a small amount of medication over an extended period of time, it can be dissolved in a bag of intravenous fluids and set on an infusion pump which delivers the medicated fluid directly into the blood. They are also commonly used to assist with surgical recovery; people who receive fluids after surgery tend to experience better recovery than people who do not. Types of Fluids • Normal Saline • Half Normal Saline • Ringers Lactate • D5W • D5W + ½% NS • 2/3 + 1/3 • Normal Plasma Form, Fill & Seal (FFS) Technology It is also an economical solution providing an inline manufacturing of the bag from a side gusseted film roll as well as filling and sealing. An automatic and precise process, environmentally safe, and cost efficient FFS gusseted tubing is water & moisture resistant, and can also be made with vapor and oxygen barrier substrates. It is both extremely durable and 100% recyclable. Advantages of FFS Gusseted Tubing Moisture & water resistant, increasing your products shelf life and reducing product waste Made from a strong and durable 3-layer film containing only the highest quality polyethylene resins with excellent sealing characteristics Easy palletizing made possible due to the shape of the filled package 8-color print capability, including 4 color process print graphics over the entire surface front, back and inside gussets to provide an eye catching product Optional built in self venting back seam labyrinth valve Compatible with existing FFS packaging machinery. SUSTAINABILITY 100% Recyclable Elimination of particle dust, creating a clean, safe and healthy environment for bagging facilities, retailers and end-users alike Increased product life cycle due to extreme barrier protection and seal strength Reduced product rework due to broken bags: less additional production and packaging required, leading to less energy and resources consumed Fewer breakages compared to traditional packaging, reducing product loss Clean in-store product presentation. FFS offers cost savings over conventional aseptic processing in glass. Traditional parental filling and packaging requires 23 steps and individual machines for filling, stoppering and capping. In contrast, FFS requires one piece of automated machinery, and takes place in six seconds or less. Market Scenario World market growth is driven by population increases and constant up-scaling and sophistication of health care delivery. As part of this up scaling, IV infusion therapy is becoming increasingly important in overall health care treatment regimens as new developments in antibiotics and other medications used in areas such as chemotherapy, burn centers, and renal/peritoneal dialysis centers favor intravenous use and application. The economic advantages of producing IV solutions locally emerging and medically in developing nations can result in an extremely short return on initial investment. Demand for IV solutions is so great that should production exceed local demand. Opportunities for national and export sales are unlimited in the foreseeable future.
Plant capacity: 9000000 No.s of Bottles (Each bottle: 1000ml)Plant & machinery: 850 Lakhs
Working capital: -T.C.I: Cost of project: 1351 Lakhs
Return: 43.00%Break even: 49.00%
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L Ascorbic Acid - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Layout

Profile L Ascorbic acid is an organic acid with antioxidant properties. Its appearance is white to light yellow crystals or powder. It is water soluble. The L enantiomer of ascorbic acid is commonly known as vitamin C. L Ascorbic acid is a versatile water soluble radical scavenger widely distributed in aerobic organisms that plays a central role in the protection of cellular components against oxidative damage by free radicals and oxidants that are involved in the development and exacerbation of a multitude of chronic diseases such as cancer, heart disease, brain dysfunction, aging, rheumatism, inflammation, stroke, emphysema, and AIDS. L Ascorbic acid (also called vitamin C) is a carbohydrate like substance involved in the metabolic functions including synthesis of collagen, maintenance of the structural strength of the blood vessels, metabolism of certain amino acids, and the synthesis or release of hormones in the adrenal glands. It occurs as a white or slightly yellow crystal or powder with a slight acidic taste. L Ascorbic Acid is freely soluble in water; sparingly soluble in alcohol; insoluble in chloroform, ether, and benzene. Properties Appearance White odourless crystalline solid Empirical formula: C6H8O6 Molecular weight: 176.1 Melting point: About 190°C (with decomposition) Source of L Ascorbic Acid The main sources of L ascorbic acid for humans are from plants and animals with indigenous biosynthetic capabilities of producing L ascorbic acid. The ubiquitousness of L-ascorbic acid throughout the human body emphasizes its daily requirement and vitality as a nutrient for healthy maintenance. Its biological half-life in humans is 14 to 40 days after normal intake and a vitamin C free diet in a human develops scurvy in about 3 to 4 months. The vast majority of species of plants and animals are known to synthesize their own vitamin C. A majority of vertebrates such as amphibians, reptiles, birds, and mammals are able to synthesize L ascorbic acid. Molecules similar to ascorbic acid are made by some fungi but not by bacteria. ? Applications Ascorbic acid (Vitamin C) is an essential nutrient that the human body cannot manufacture from other compounds. • It is needed for the formation of collagen, the protein that makes up connective tissue, and is essential to muscles, bones, cartilage, and blood vessels. • Ascorbic acid is also a good anti-oxidant, preventing damage from oxygen free radicals. • Ascorbic acid (vitamin C) is used extensively in the food industry, not only for its nutritional value but for its many functional contributions to product quality. • Acting as an antioxidant, ascorbic acid can improve the color and palatability of many kinds of food products. By removing oxygen from its surroundings, ascorbic acid in its reduced form becomes the oxidized form, de hydro ascorbic acid (see in the fig). This oxidizing action reduces the available oxygen in its immediate environment, making ascorbic acid an effective antioxidant. • L ascorbic acid or L ascorbate is a vital nutrient for many animals, including humans. It is an antioxidant which protects the body against oxidative stress. Market Scenario Ascorbic acid is major food ingredients, and also plays a major role in the fermentation industry. In the past ten years, the markets for these products have changed dramatically. The demand for ascorbic acid in food and non food applications has increased continuously and substantial capacities have been built up. The global market for isoascorbic acid, ascorbic acid and citric acid is estimated at $1,700 million. Food applications account for $1,080 million, feed applications for $90 million. Chinese producers currently have a market share of 37% in isoascorbic acid, 65% in ascorbic acid and 34% in citric acid. Sales of isoascorbic acid will grow at an average annual growth rate (AAGR) of 2.9%. The European market for citric acid accounts for a total of 37% of sales and the U.S. market for 28% of sales. Current world production is estimated at approximately 80,000 metric tons per year with a worldwide market in excess of $600 million. It is synthesized both biologically and chemically from D glucose. ?
Plant capacity: 240 MT/AnnumPlant & machinery: 72 Lakhs
Working capital: -T.C.I: Cost of project : 211 Lakhs
Return: 42.00%Break even: 58.00%
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Pharmaceutical Unit - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

Profile The Indian Pharmaceutical Industry today is in the front rank of Indias science-based industry with wide ranging capabilities in the complex field of drug manufacture and technology. A highly organized sector, the Indian Pharmaceutical Industry is estimated to be worth $ 4.5 billion, growing at about 8 to 9 percent annually. It ranks very high in the third world, in terms of technology, quality and range of medicines manufactured. From simple headache pills to sophisticated antibiotics and complex cardiac compounds, almost every type of medicine is now made indigenously. Properties of Drugs & Formulation Physical property generally refers to the form or behaviour of a given kind of matter so long as its chemical composition remains unchanged, the drug matter, like many other matters, has their physical characteristics. The accumulated experience of the preparation of dosage forms indicates that some of these physical properties could have important as in the design of the dosage forms. The structure of a drug molecule and its pharmacological activity are highly inter-related phenomena. Some compounds such as local anesthetics or morphine, on the other hand, undergo appreciable modification without serious loss of fundamental activity. One of the supreme objectives of a formulation has to be that the chemical configuration of the drug molecule and total chemical composition of the formulation must maintain a status. Market Potential The Indian pharmaceutical industry is the fourth largest in the world in terms of volume of output and thirteenth in domestic demand. However, the Indian industry, valued at USD 17 bn in represented just over 1% of the global pharmaceutical industry (USD 1700 bn) in value terms. The domestic market is estimated at Rs 680 bn. The Indian Pharmaceutical sector is highly fragmented with more than 20,000 registered units. It has expanded drastically in the last two decades. The leading 250 pharmaceutical companies control 70% of the market with market leader holding nearly 7% of the market share. The pharmaceutical industry has been one of the fastest growing segments of the Indian manufacturing sector with an average annual growth rate of about 14% during the quinquennium 2002-2007. It is projected to grow at an average annual rate exceeding 15% during 2007-2010 and is likely to reach the level of about USD 23 to 28 bn in 2010. Cost Estimation: Capacity : 90 Lakh Bruphen Tablets/Annum 90 Lakh Vitamin Capsules/Annum 30 Lakh Paracetamol Syrup Bottles/Annum 18 Lakh Dextrose Saline Bottles/Annum 18 Lakh Streptomycin Injection/ Annum
Plant capacity: -Plant & machinery: 294 Lakh
Working capital: -T.C.I: Cost of Project : 827 Lakh
Return: 44.00%Break even: 53.00%
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PHARMACEUTICAL UNIT (TABLETS, SYRUP, CAPSULES & OINTMENT) - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Plant Layout

Profile The pharmaceutical unit develops, produces, and markets drugs licensed for use as medications. Pharmaceutical companies are allowed to deal in generic and/or brand medications and medical devices. The Indian pharmaceutical sector has come a long way, being almost non existent before 1970 to a prominent provider of healthcare products, meeting almost 95 per cent of the country's pharmaceuticals needs. The Industry today is in the front rank of Indias science based industries with wide ranging capabilities in the complex field of drug manufacture and technology. It ranks very high in the third world, in terms of technology, quality and range of medicines manufactured. From simple headache pills to sophisticated antibiotics and complex cardiac compounds, almost every type of medicine is now made indigenously. Benefits Pharmaceutical companies are manufacturing vaccines to prevent individuals from catching diseases and to strengthen their immune systems. They activate and enhance the efficiency of the human immune system to help prevent infections. These preventive measures are low priced, constantly effective and easy to store. These vaccines can be carried and transported from one place to another with ease. A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease. Market Scenario The Indian Pharmaceutical sector is highly fragmented with more than 20,000 registered units. It has expanded drastically in the last two decades. The leading 250 pharmaceutical companies control 70% of the market, with market leader holding nearly 7% of the market share. It is an extremely fragmented market with severe price competition and government price control. The pharmaceutical industry in India meets around 70% of the countrys demand for bulk drugs, drug intermediates, pharmaceutical formulations, chemicals, tablets, capsules, orals and injectables. There are about 250 large units and about 8000 Small Scale Units, which form the core of the pharmaceutical industry in India (including 5 Central Public Sector Units). Cost Estimation: Capacity : 15 Lakh Tablets/day 15 Lakh Capsules/day 25000 Syrup Bottles/day 20000 Ointment Tubes/day Plant and Machinery : 385 Lakh Total capital Investment : 3248 Lakh Rate of return : 104% Break Even Point : 46%
Plant capacity: -Plant & machinery: 385 Lakh
Working capital: -T.C.I: 3248 Lakh
Return: 104.00%Break even: 46.00%
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ORLISTAT - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue, Plant Economics

Profile Orlistat also known as tetrahydrolipstatin, is a drug designed to treat obesity. It is a hydrogenated derivative of lipstatin and an inhibitor of gastrointestinal lipases produced by chemical synthesis. Orlistat is an anti obesity drug, that promotes loss of weight by preventing the digestion and absorption of fat in food. In the intestine, an enzyme called lipase (produced primarily by the pancreas) breaks apart fat in food, so that it can be absorbed into the body. Orlistat blocks the action of lipase and thereby prevents the breakup and absorption of fat. Properties Chemical name - Orlistat CAS number - 96829-58-2 Chemical Formula - C29H53NO5 Appearance - White powder Solubility - Insoluble in water Stability - More stable under alkaline conditions. Melting point - 42 deg C Application Orlistat is a lipase inhibitor for obesity management that acts by inhibiting the absorption of dietary fats. At the recommended therapeutic dose of 120 mg three times a day, orlistat inhibits dietary fat absorption by approximately 30%. It works by inhibiting pancreatic lipase, an enzyme that breaks down fat in the intestine. Without this enzyme, fat from the diet is excreted undigested and not absorbed by the body. Because some vitamins are fat soluble, the effect of orlistat is to reduce their body absorption. Orlistat may reduce plasma levels of ciclosporin (also known as "cyclosporin" or "cyclosporine", trade names Sandimmune, Gengraf, Neoral, etc.), an immunosuppressive drug frequently used to prevent transplant rejection; the two drugs should therefore not be administered concomitantly. Orlistat can also impair absorption of the antiarrhythmic amiodarone. Market Scenario Due to huge national population in India and its increasing trend as well as the rising incidents of lifestyle diseases, obesity would continue to remain as a major health problem in India for significant size of population. Orlistat (prescription and nonprescription) is used with an individualized low-calorie, low-fat diet and exercise program to help people lose weight. Prescription orlistat is used in overweight people who may also have high blood pressure, diabetes, high cholesterol, or heart disease. Orlistat is also used after weight-loss to help people keep from gaining back that weight. Orlistat is in a class of medications called lipase inhibitors. It works by preventing some of the fat in foods eaten from being absorbed in the intestines. Hence it has a huge demand.
Plant capacity: -Plant & machinery: -
Working capital: -T.C.I: -
Return: 0.01%Break even: N/A
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Invert Sugar Enzyme Based - Manufacturing Plant, Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Manufacturing Process, Machinery, Raw Materials, Feasibility Study, Investment Opportunities, Cost and Revenue

Invert Sugar (invert sugar syrup) is pale (golden yellow) colored sweetener prepared by the acid hydrolysis/enzymatic hydrolysis of a solution of white refined sugar. Invert Sugar Syrup or Invert Syrup as it is commonly known; is an equimolecular ratio of glucose and fructose in aqueous form. The Product is made from cane sugar or cane juice. Invert sugar contains equal proportions of the invert (reducing) sugars: glucose and fructose. It has wide application and is particularly useful where high concentrations of invert sugars are required. The crystal inhibiting characteristics and humectants property (retention of moisture) means that the shelf life of many products can be extended by the use of Invert Syrup in product formulations. It has a high degree of sweetening power relative to sucrose. APPLICATION: Invert sugar has its application in many industries such as beverage & distillery industries, bakery & general industries, tobacco industries, honey industries, pharmaceutical industries etc. Invert sugar is used to substitute granulated sugar or honey between 10 and 50% of its weight according to desired usage or effect. Apart from that, invert sugar has double the bacteriological potential of sucrose therefore reducing the need for preservatives. Invert sugar can be used in any recipes that contain granulated sugar, which is well known for its hardening effect on the products it is found in. In addition, invert sugar absorbs water and retains it, which is why it is a good humidifying agent as it keeps dishes moist for much longer. It can also be used in any confectionery or ice cream formula to partially substitute granulated sugar and also honey in certain specialties Invert sugar can be used in combination with other humidifying agents, increasing its ability to retain moisture, for caramelization and enhanced flavor. Market Survey: The Invert sugar is greater in demand than pure glucose as food and drink sweeteners, because fructose is sweeter than glucose. Main consumers of Invert Sugar are the baking, beverages, canning, confectionery and dairy industries.
Plant capacity: 3000 MT/AnnumPlant & machinery: 127 Lakhs
Working capital: -T.C.I: 389 Lakhs
Return: 25.39%Break even: 61.86%
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  • One Lac / Lakh / Lakhs is equivalent to one hundred thousand (100,000)
  • One Crore is equivalent to ten million (10,000,000)
  • T.C.I is Total Capital Investment
  • We can modify the project capacity and project cost as per your requirement.
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  • Caution: The project's cost, capacity and return are subject to change without any notice. Future projects may have different values of project cost, capacity or return.

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