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Manufacturing Of Artemisinin From Artemisia Annua Plant. Increasing The Strength And Production Of Artemisinin. | |
| Artemisinin is a medicine made from Artemisia annua, an Asian plant. The leaves of this aromatic plant resemble ferns, while the flowers are yellow. Artemisia annua is also known by the following names: 1. Qinghaosu 2. Qing Hao 3. Sweet Wormwood 4. Sweet Annie 5. Sweet Sagewort 6. Annual Wormwood Artemisinins, which are obtained from extracts of sweet wormwood (Artemisia annua), are well-known for treating malaria, even in drug-resistant forms. Their effectiveness also extends to parasitic illnesses that are phylogenetically unrelated, such as schistosomiasis. They've also been found to have robust and wide anticancer activities in cell lines and animal models recently. Sweet wormwood, sweet Annie, and qinghao are all common names for Artemisia annua, a shrub native to China that has long been utilised for both ornamental and medicinal uses. A. annua is now grown all over the world as the only source of artemisinin, a powerful anti-malarial medicine. The drug is part of a cocktail of phytochemicals stored in glands on the epidermis of the leaves, known as "glandular trichomes," and utilised to keep browsers away. Artemisinin has proven to be effective against the highly adaptable malaria parasite, which has already developed resistance to a number of other medications. Because of its great potency, rapid clinical and parasitological response, efficacy against diverse parasite stages, and low toxicity, artemisinin derivatives are at the heart of contemporary malaria treatment. They contain a variety of lipophilic—artemether and arteether for intramuscular usage, as well as artemether capsules for oral administration — as well as water-soluble chemicals like artesunate (AS), which can be administered orally, through injection, or as suppositories. All are converted to the active ingredient, dihydroartemisinin (DHA), which is also available as an oral formulation, after administration. Artemisinin derivatives have a short half-life and are quickly removed from the body. They were first used as a single treatment for the condition. Plasmodium falciparum malaria is treated with artemisinin combination therapy (ACT). Due to the significant prevalence of malaria, especially in emerging and underdeveloped nations, this market has been growing in recent years. Because of its expanding application scope in the pharmaceutical industry, the worldwide artemisinin market is predicted to increase significantly over the period. WHO recognition of artemisinin-based combination therapy (ACT) as a first-line treatment for malaria, demand for artemisinin has increased significantly over the last decade. Because of the huge production base of artemisinin herbs and the growing need for artemisinin-based therapy in malaria-endemic areas, Asia Pacific and Africa held the greatest market share for artemisinin and its derivatives. The largest consumer regions are Europe and India. In 2015, Europe's consumption was estimated to be around 107 MT. India's consumption has fluctuated in recent years, accounting for roughly 26% of total in 2015. Major Players: 1. Fosun Pharmaceutical (Guilin Pharmaceutical) 2. Sanofi S.A. 3. Novartis AG 4. KPC Pharmaceuticals 5. Cipla Ltd. | |
| Plant capacity: - | Plant & machinery: - |
| Working capital: - | T.C.I: - |
| Return: 1.00% | Break even: N/A |
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