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Investment Opportunities In Business Of 7-aminocephalosporanic Acid (7-aca)

7-ACA is a significant nucleus in the synthesis of cephalosporin antibiotics; the nucleus 7 and 3 chemical transformation may be utilised to prepare numerous cephalosporins, including cefazolin sodium, cefotaxime sodium, ceftriaxone sodium, cefoperazone sodium, sodium ceftazidime, and cefuroxime sodium. 7-ACA is a crucial step in the API synthesis that is formed via (bio- chemical) derivatization at positions 3? and 7?. Cephalosporin C can be transformed to 7-ACA by removing the 7-amino adipoyl side chain either chemically or enzymatically. 3-(Acetyloxy-methyl)-7-amino-8-oxo-5-thia-1-azabicyclo (4.2.0) oct-2-ene-2-carboxylic acid [chemically, 3-(Acetyloxy-methyl)-7-amino-8-oxo-5-thia-1-azabicyclo (4.2.0) oct-2-ene-2-carboxylic acid] for the synthesis of cephalosporins and intermediates, is the active nucleus. - Inhibitor of bacterial -lactamase (S. aureus). - Bacterial transpeptidase inhibitor; antibacterial Antibiotics are antibiotics that are used to treat bacterial infections. Infections in the respiratory and urinary systems, as well as the skin and bones, are treated with this antibiotic. Indian pharmaceutical companies now provide virtually all of the country's formulations and over 70% of its bulk drug needs. Between 350 and 400 bulk pharmaceuticals are produced by Indian companies, which create almost 60,000 generic brands in 60 therapeutic areas. India's pharma market is dominated by second and third generation medications that are no longer protected by patents in the developed nations. India has the world's third largest active pharmaceutical ingredients (API) market, worth little under USD 2 billion. About 6.5 percent of APIs are produced by the top five companies. Antibiotics, gastrointestinal, cardiovascular, and respiratory APIs are the most common. As patented blockbuster pharmaceuticals lose their patent protection, the Chemical Pharmaceutical Generic Association (CPA) predicts that India's share of the global API industry will expand by 10.5 percent by 2010. The CPA also forecasts an increase in the local Indian market for APIs, both generic and branded, from USD 755 million in 2005 to USD 1.9 billion in 2010. India's API market is expected to develop at a rate of 10.76 percent each year. As a whole there is a good scope for new entrepreneur to invest in this business.
Plant capacity: 7-Aminocephalosporanic Acid 0.5 MT per DayPlant & machinery: 593 Lakhs
Working capital: -T.C.I: Cost of Project: 1937 Lakhs
Return: 28.00%Break even: 45.00%
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