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Soft And Hard Gelatin Capsules (vegetable And Non Veg. Base)

A capsule is a shell or a container prepared from gelatin containing one or more medicinal and/or inert substances. The gelatin capsule shell may be soft or hard depending on their formulation. The term capsule derived from the Latin Capsula meaning small box. In 1833, Mothes first introduced the soft capsule (soft gel), which then in 1838 the invention is patentable. Hard Gelatin itself is discovered by Lehuby in 1846. Capsule can be used for internal usage (orally, through the nose, through the body cavity) and external usage (outside of the body). Capsule is a solid particle which has a size of 0.1 to 10,000 ?. According to the pharmacopoeia of Indonesia, the capsule is a solid dosage of the drug in hard or soft shell that can be dissolved. Shells are generally made of gelatin, can also be made from starch or other suitable material. Gelatin is defined as a product obtained by the partial hydrolysis of collagen derived from the skin white connective tissue and bones of animals. Gelatin derived from an acid treated pre curser is known as type A and gelatin derived from an alkali treated precursor is known as type B. Gelatin is a protein and in aqueous solution forms a hydrophilic colloid, leading to complex behavior. As a normal constituent of plant and animal tissues, it is essential to their growth. It occurs especially in seeds, the yolk of eggs, the nerves and brain and bone narrow, usually in the form of lecithins or glycero phosphates. It is an essential constituent of bones in the format calcium phosphate. Bone contains about 58% calcium phosphate plus some calcium carbonate, fat and nitrogenous organic matter. Technical gelatin generally refers to the gelatin that is used for non edible purposes. Uses & Applications The industry recognizes four different kinds of gelatin, edible, technical, photographic and pharmaceutical. Gelatin is widely consumed food, and it is popular dessert which is easily assimilated and even helps in the digestion of other foods by forming an emulsion with fats and proteins. Gelatin has played an important part in the rapid development of the motion picture and photographic industry. It is coated on the film base, constituting the sensitized emulsion of the light sensitive silver salts. Technical gelatin is quite an arbitrary name applied to small amounts used for miscellaneous purposes, such as for sizing paper, textiles and straw hats. Gelatin is used by pharmaceutical houses for making capsules and as an emulsifier. Advantages of Hard and Soft Gelatin Capsule Hard: Rapid drug release possible, Flexibility of formulation, Sealed HGCs are good barriers to atmospheric oxygen. Soft : High Accuracy/precision possible, Hermetically sealed (inherently), Possible bioavailability advantages, Reduced dustiness; lack of compression stage in manufacture, Possible reduced gastric irritancy compared to tablets and hard shell capsules, Specialty packages available. Market Survey Today Gelatin is a vital ingredient in the most popular drug delivery systems in the world such as two piece hard capsules, soft capsules, tablets, coated tablets, mini, micro capsules etc. The global gelatine market is set to continue its rise with gelatine consumption forecast to reach 395.84 thousand metric tons by 2017. Continued growth in the gelatine market is being fuelled by an aging population, focus on healthcare and increasing demand from end use industries such as food & beverage, nutraceuticals and pharmaceuticals. US based global industry Analysts( GIA) said the global gelatin market is growing fast the farm estimates that it will reach 357800 metric tons by 2015 driven by increasing demand for gelatin as bio material in cosmetics and from developing countries. Few Indian Major Players are as Under: A B L Biotechnologies Ltd. A C G Arts & Properties Pvt. Ltd. Capsugel Healthcare Ltd. Chemcaps Ltd. Dinesh Remedies Ltd. Healthcaps India Ltd. Medi Caps Ltd. Natural Capsules Ltd. Sunil Healthcare Ltd.
Plant capacity: 2880000 Nos. /dayPlant & machinery: 397 Lakhs
Working capital: -T.C.I: 637 Lakhs
Return: 36.00%Break even: 43.00%
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